为答谢和回馈广大科研工作者们长期以来对武汉快盈科技有限公司的大力支持，快盈科技联合细胞骨架领域顶级供应商Cytoskeleton联合推出：小G蛋白&GEF产品线超值大促，一年仅此一次，千万不要错过啊！本次促销活动产品涵盖 GEFs, 小G蛋白和 G-LISA活化试剂盒等。
小G蛋白(Small G Protein)因分子量只有20—30KD 而得名，同时具有GTP酶活性，在细胞信号通路中发挥分子开关的功能，参与调控很多生物学过程，包括分泌活动和细胞骨架的装配等。目前发现的小G蛋白包括Rho, Rac, Arf1 & 6, Ras, Ral等。小G蛋白的共同特点是，当结合了GTP时即成为活化形式，这时可作用于下游分子使之活化，而当GTP水解成为GDP时（自身为GTP酶）则恢复到非活化状态。
Pull-down和G-LISA实验都被广泛地用于研究小G蛋白的活性。Pull-down实验又叫蛋白质体外结合实验，可用于测定活性的GTPase亚型，可作为对G-LISA实验的补充。G-LISA实验是一种改进的ELISA，可测定3D细胞系、原代细胞裂解液及组织裂解液中有活性的GTPase，使GTPase定量的准确性增加。
活动详情：
时间：2025年5月20日-2025年6月30日
对象：仅限中国区终端客户
品目：GEFs, 小G蛋白和G-LISA活化试剂盒等产品（详情见下方活动品目列表）
内容： 直享 6.5 折超低优惠！
活动品目列表：
| 类别 | 货号 | 产品名称 | 规格 | 原价 | 促销价 |
| 抗体 | CSK-ACD04 | Anti-Cdc42 Mouse Monoclonal Antibody | 1x500ul | 6550 | 4258 |
| CSK-ACD04-S | Anti-Cdc42 Mouse Monoclonal Antibody (sample size) | 1x125ul | 1772 | 1152 | |
| CSK-ARC03 | Anti-Rac1 specific mouse MAb | 2x100ul | 6396 | 4158 | |
| CSK-ARC03-S | Anti-Rac1 specific mouse MAb(sample size) | 1x25ul | 1772 | 1152 | |
| 试剂盒 | CSK-BK008 | Ras Activation Assay Biochem Kit | KIT50assays | 13717 | 8916 |
| CSK-BK008-S | Ras Activation Assay Biochem Kit | KIT20assays | 6319 | 4108 | |
| CSK-BK030 | Combo RhoA/Rac1/Cdc42 Activation Assay Kit | KIT3x10assays | 16646 | 10820 | |
| CSK-BK032-S | Arf1 Pulldown Activation Assay Kit | KIT20assays | 8169 | 5310 | |
| CSK-BK033-S | Arf6 Pulldown Activation Assay Kit | KIT20assays | 8169 | 5310 | |
| CSK-BK034 | Cdc42 Pulldown Activation Assay Kit | KIT50assays | 13717 | 8916 | |
| CSK-BK034-S | Cdc42 Pulldown Activation Assay Kit | KIT20assays | 6319 | 4108 | |
| CSK-BK035 | Rac1 Pulldown Activation Assay Kit | KIT50assays | 13717 | 8916 | |
| CSK-BK035-S | Rac1 Pulldown Activation Assay Kit | KIT20assays | 6319 | 4108 | |
| CSK-BK036 | RhoA Pulldown Activation Assay Kit | KIT80assays | 13717 | 8916 | |
| CSK-BK036-S | RhoA Pulldown Activation Assay Kit | KIT20assays | 6319 | 4108 | |
| CSK-BK100 | Rho GEF Exchange Assay | KIT60-300assays | 11560 | 7514 | |
| CSK-BK105 | GAP Assay Kit | KIT80-160assays | 11560 | 7514 | |
| CSK-BK121 | RhoA G-LISA Activation Assay (luminescence) | KIT96assays | 15367 | 9988 | |
| CSK-BK124 | RhoA G-LISA Activation Assay (colorimetric) | KIT96assays | 15367 | 9988 | |
| CSK-BK124-S | RhoA G-LISA Activation Assay (colorimetric) | KIT24assays | 9633 | 6261 | |
| CSK-BK125 | Rac1,2,3 G-LISA Activation Assay Kit (colorimetric) | KIT96assays | 15367 | 9988 | |
| CSK-BK126 | Rac1 G-LISA Activation Assay Kit | KIT96assays | 15367 | 9988 | |
| CSK-BK127 | Cdc42 G-LISA Activation Assay Kit (colorimetric) | KIT96assays | 15367 | 9988 | |
| CSK-BK127-S | Cdc42 G-LISA Activation Assay Kit (colorimetric) | KIT24assays | 9633 | 6261 | |
| CSK-BK128 | Rac1 G-LISA Activation Assay Kit (colorimetric) | KIT96assays | 15367 | 9988 | |
| CSK-BK128-S | Rac1 G-LISA Activation Assay Kit (colorimetric) | KIT24assays | 9633 | 6261 | |
| CSK-BK129 | RalA G-LISA Activation Assay Kit (colorimetric) | KIT96assays | 15367 | 9988 | |
| CSK-BK131 | Ras G-LISA Activation Assay Kit (colorimetric) | KIT96assays | 15367 | 9988 | |
| CSK-BK135 | G-LISA Bundle (BK135 = BK124-S + BK127-S + BK128-S) (colorimetric) | 3KITS(24assays/kit) | 27435 | 17833 | |
| CSK-BK150 | RhoA ELISA Kit (colorimetric) | KIT96assays | 8631 | 5610 | |
| 蛋白 | CSK-C17G01-A | Cdc42-GST protein: dominant negative | 1x25ug | 7013 | 4558 |
| CSK-C6101-A | Cdc42-His Protein: constituitively active | 1x10ug | 7013 | 4558 | |
| CSK-CD01-A | Cdc42-His Protein: Wild type | 1x100ug | 7013 | 4558 | |
| CSK-CD01-C | Cdc42-His Protein: Wild type | 3x100ug | 12561 | 8165 | |
| CSK-CD01-XL | Cdc42-His Protein: Wild type | 1x1mg | 24815 | 16129 | |
| CSK-CDG01-XL | Cdc42-GST Protein: Wild type | 1x1mg | 19266 | 12523 | |
| CSK-CS-GE03 | Ras-GRF GEF protein (human recomb. CDC25 domain, MBP tagged) | 1x100ug | 6705 | 4358 | |
| CSK-CS-GE04 | Tiam1 GEF protein (human recomb. DHPH domain, MBP tagged) | 1x100ug | 6705 | 4358 | |
| CSK-CS-GE05 | Vav1 GEF protein (human recomb. DHPHC1 domain Y174D mutant, 6xHis tagged) | 1x100ug | 6705 | 4358 | |
| CSK-CS-GE06 | Vav2 GEF protein (human recomb. DH domain, 6xHis tagged) | 1x100ug | 6705 | 4358 | |
| CSK-CS-GE07 | ARNO Protein: GEF (Sec7) domain (aa31- 267, human recomb., 6xHis tagged) | 1x100ug | 6705 | 4358 | |
| CSK-CS-GE08 | SOS2 exchange domain (563-1051) protein (Human recombinant) | 1x100ug | 6705 | 4358 | |
| CSK-CS-GE09 | RAPGEF5 Protein: Ras association and exchange domain (57– 580) wild type. (Human recombinant, GST tagged) | 1x100ug | 6705 | 4358 | |
| CSK-CS-GE10 | SOS1 Exchange Domain (564-1049) Protein : GST-Tagged (Human Recombinant) | 1x100ug | 6705 | 4358 | |
| CSK-CS-RS02 | N-Ras Protein; wild-type (human recombinant with 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CS-RS03 | K-Ras4B Protein: wild-type (human recombinant with 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CS-RS04 | K-Ras4B Mutant Protein: G12V (human recombinant with 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CS-RS05 | R-Ras Protein: wild-type (human recombinant with 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CS-RS06 | K-Ras4B Mutant Protein: G13D (human recombinant with 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CS-RS07 | K-Ras4B Mutant Protein: G13S (human recombinant with 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CS-RS08 | K-Ras4B Mutant Protein: K128A (human recombinant with 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CS-RS09 | K-Ras4B Mutant Protein: Q61P (human recombinant with 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CS-RS10 | K-Ras4B Mutant Protein: R135A (human recombinant with 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CS-RS11 | K-Ras4B Mutant Protein: G12D+I36N (human recombinant with 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CS-RS12 | K-Ras4B Mutant Protein: G12D+D38A (human recombinant with 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CS-RS13 | K-Ras4B Mutant Protein: G12D (human recombinant with 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CS-RS14 | K-Ras4B G12C mutated protein (Human recombinant, 6xHis-tag) | 1x100ug | 7090 | 4608 | |
| CSK-CT03-A | C3 transferase protein | 1x25ug | 3468 | 2254 | |
| CSK-CT03-C | C3 transferase protein | 4x25ug | 12716 | 8265 | |
| CSK-CT04-A | Cell Permeable Rho Inhibitor (C3 Trans based)) | 1x20ug | 3468 | 2254 | |
| CSK-CT04-B | Cell Permeable Rho Inhibitor (C3 Trans based)) | 5x20ug | 11405 | 7414 | |
| CSK-CT04-C | Cell Permeable Rho Inhibitor (C3 Trans based)) | 20x20ug | 28128 | 18283 | |
| CSK-GAP01-A | Rho GAP Protein GST | 1x50ug | 5009 | 3256 | |
| CSK-GAP01-B | Rho GAP Protein GST | 4x50ug | 13101 | 8516 | |
| CSK-GAS01-A | Rho GAP Protein: catalytic domain GST | 1x50ug | 5009 | 3256 | |
| CSK-GAS01-B | Rho GAP Protein: catalytic domain GST | 4x50ug | 13101 | 8516 | |
| CSK-GDI01-A | GDP dissociation inhibitor protein GST fusion | 1x25ug | 5009 | 3256 | |
| CSK-GE01-A | Dbs protein GEF domain - HIS fusion | 2x50ug | 5009 | 3256 | |
| CSK-GE02 | SOS1 Ras GEF protein (human recomb. ExD domain, 6xHis tagged) | 1x100ug | 6705 | 4358 | |
| CSK-GE02-XL | SOS1 Ras GEF protein (human recomb. ExD domain, 6xHis tagged) | 1x1mg | 29593 | 19235 | |
| CSK-GGA07-A | GGA3-PBD Arf Affinity Beads | 1x500ug | 9787 | 6362 | |
| CSK-PAK01-A | PAK Rac1/Cdc42 binding domain protein | 1x250ug | 6782 | 4408 | |
| CSK-PAK01-B | PAK Rac1/Cdc42 binding domain protein | 4x250ug | 18033 | 11721 | |
| CSK-PAK02-A | PAK Beads, Rac1/Cdc42 binding domain protein on beads | 2x500ug | 7552 | 4909 | |
| CSK-PAK02-B | PAK Beads, Rac1/Cdc42 binding domain protein on beads | 6x500ug | 21886 | 14226 | |
| CSK-R17G01-A | Rac1 GST Protein: dominant negative | 1x25ug | 7013 | 4558 | |
| CSK-R6101-A | Rac1 His Protein: constitutively active | 1x10ug | 7013 | 4558 | |
| CSK-R6301-A | RhoA His Protein: constitutively active | 1x10ug | 7013 | 4558 | |
| CSK-RC01-A | Rac1 His Protein: wild type | 1x100ug | 7013 | 4558 | |
| CSK-RC01-C | Rac1 His Protein: wild type | 3x100ug | 12716 | 8265 | |
| CSK-RC01-XL | Rac1 His Protein: wild type | 1x1mg | 25046 | 16280 | |
| CSK-RC02-A | Rac2 His Protein: wild type | 1x100ug | 7013 | 4558 | |
| CSK-RCG01-C | Rac1 GST Protein: wild type | 8x25ug | 11097 | 7213 | |
| CSK-RF02-A | Raf protein ras binding domain on GST beads | 2x2mg | 8323 | 5410 | |
| CSK-RF02-B | Raf protein ras binding domain on GST beads | 6x2mg | 23890 | 15528 | |
| CSK-RH01-A | RhoA His Protein: wild type | 1x100ug | 7013 | 4558 | |
| CSK-RH01-C | RhoA His Protein: wild type | 3x100ug | 12716 | 8265 | |
| CSK-RH01-XL | RhoA His Protein: wild type | 1x1mg | 25046 | 16280 | |
| CSK-RH03-A | RhoC His Protein: wild type | 1x100ug | 7013 | 4558 | |
| CSK-RHG01-C | RhoA GST Protein: wild type | 8x25ug | 10327 | 6712 | |
| CSK-RR02-A | Rap1b protein (Human wild type, His) | 1x100ug | 7013 | 4558 | |
| CSK-RS01-A | H-Ras Protein; wild type 6xHis Tag | 1x100ug | 7013 | 4558 | |
| CSK-RS01-C | H-Ras Protein; wild type 6xHis Tag | 3x100ug | 12716 | 8265 | |
| CSK-RT01-A | Rhotekin RBD protein GST fusion | 1x500ug | 7861 | 5109 | |
| CSK-RT02-A | Rhotekin RBD protein on GST beads | 2x2mg | 11097 | 7213 | |
| CSK-RT02-B | Rhotekin RBD protein on GST beads | 6x2mg | 24660 | 16029 | |
| CSK-VCG03-A | VCA domain of WASP (GST fusion) | 1x500ug | 8477 | 5510 | |
| 抑制剂&激活剂 | CSK-CN01-A | Rho Activator | 5x10units | 3622 | 2354 |
| CSK-CN01-B | Rho Activator | 20x10units | 12947 | 8415 | |
| CSK-CN02-A | Rac and Cdc42 Activator | 5x10units | 3622 | 2354 | |
| CSK-CN02-B | Rac and Cdc42 Activator | 20x10units | 12947 | 8415 | |
| CSK-CN03-A | Rho activator II | 3x20ug | 3622 | 2354 | |
| CSK-CN03-B | Rho activator II | 9x20ug | 10172 | 6612 | |
| CSK-CN04-A | Rho/Rac/Cdc42 Activator I | 3x20ug | 3622 | 2354 | |
| CSK-CN04-B | Rho/Rac/Cdc42 Activator I | 9x20ug | 10172 | 6612 |
* 本活动最终解释权归快盈科技所有
Cytoskeleton公司成立于1993年，专注于生物化学和细胞过程研究中的纯化蛋白和便捷试剂盒开发与生产。公司提供药物筛选、信号转导、蛋白质转录后修饰（PTM）、细胞骨架研究相关的系列试剂盒和产品，尤其以细胞骨架相关研究见长，既能满足于样品较少的科学研究，也可以用于小规模筛选研究和高通量大规模筛选研究。
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